Pratap Challa, MD
Associate Professor of Ophthalmology, Glaucoma Division Residency Program Director
We are happy that you are considering Duke Eye Center for your residency in ophthalmology. We are a well-established program with over 70 faculty members in all subspecialties. Our over 200 graduates have gone on to careers in academic and private ophthalmology practices, and have continued to advance clinical practice and basic science.
Our residents receive world-class training in medical and surgical treatment of eye diseases, and participate in research, presenting at national and international conferences. Above all, they enjoy a supportive environment in which to develop their knowledge and skills in the top-rated Duke University Hospital in Durham, North Carolina, one of the country’s most livable cities.
Pratap Challa, MD, specializes in glaucoma management including medical, laser, and surgical treatments for glaucoma. He is experienced in all forms of glaucoma surgery, including trabeculectomy with antimetabolite therapy, tube implants, cataracts, and revision of glaucoma surgery. Challa is also the director of the Duke University residency program and oversees resident training and education.
As a physician-scientist investigator, Challa has a special research interest in the genetic basis of inherited eye diseases. He investigates the genetic basis and cause for pseudoexfoliation syndrome and pseudoexfoliation-associated glaucoma. He actively recruits patients to participate in these studies and investigates the molecular basis for these disorders. He also has a novel drug delivery program involved in developing long-term delivery devices for glaucoma medications. He also investigates novel compounds that may eventually be used for treating glaucoma.
Challa's primary research interests are directed at both basic science and clinical research in the subspecialty of glaucoma. His basic science interests are on the genetic basis of inherited eye disorders. He is focused on examining transcriptional profiles in disorders such as Pseudoexfoliation Syndrome (PEX). PEX is one of the leading causes of glaucoma worldwide. This research is aimed at identifying candidate genes for several types of glaucoma. He also has research interests in the development of novel drug delivery devices and new drug therapies, such as peptide-based therapies for glaucoma. In addition to basic science research, he also has clinical research interests including evaluating the effectiveness of new glaucoma therapies.