At Duke University, in collaboration with Prof. Cynthia A. Toth, director of the Duke Advanced Research in Spectral Domain OCT Imaging (DARSI) Laboratory, we investigate how to improve early diagnostic methods, and find new imaging biomarkers for both age-related macular degeneration (AMD) and for retinal diseases in children. Along with Dr. Toth and Prof. Joseph A. Izatt, director of the Laboratory for Biophotonics, we are focused on applying spectral domain optical coherence tomography (SDOCT) systems to the study of retinal diseases at the bedside or in the operation room.    

 

On another front, we study efficient signal processing based methods to overcome the theoretical and practical limitations that constrain the achievable resolution of any imaging device. Our approach which is based on adaptive extraction and robust fusion of relevant information from the expensive and sophisticated as well as simple and cheap sensors, has found wide applications in improving the quality of imaging systems such as ophthalmic SDOCT, digital X-ray mammography, electronic and optical microscopes, and commercial digital camcorders.