Tatiana Rebrik, PhD

Tatiana Rebrik, PhD, is focused in her research on the mechanisms of phototransduction and light adaptation in cone photoreceptors. In electrophysiological experiments on isolated cone photoreceptors, we have discovered and characterized a cone-specific Ca2+ -dependent modulation of the cGMP-gated channels, an important molecular mechanism involved in the light adaptation in cones, but the molecular identity of this protein remained unknown. Recently we have identified a novel protein that acts as a modulator of a cone cGMP-gated channel.