Pratap Challa

Associate Professor of Ophthalmology
Campus mail: Box 3802 Med Ctr, Durham, NC 27710
Phone: (919) 681-2793

As a physician-scientist investigator, Dr. Challa has a special research interest in the genetic basis of inherited eye diseases. He has active projects investigating the genetics of Pseudoexfoliation associated glaucoma and the cellular basis for glaucoma development. He also studies ocular drug delivery and is involved in developing long-term delivery devices for glaucoma medications. He also investigates novel compounds that may eventually be used for treating glaucoma. In addition to basic science research, he also has clinical research interests including evaluating the effectiveness of new glaucoma therapies.

Education and Training

  • University of Florida, M.D. 1993


Human aqueous humor exosomes.

Aqueous humor (AH) is a dynamic intraocular fluid that supports the vitality of tissues that regulate intraocular pressure. We recently discovered that extracellular nanovesicles called exosomes are a major constituent of AH.