Duke VIP lab is the largest ophthalmology database in the world and is led by Felipe Medeiros, MD, PhD and Research Scientist, Alessandro Jammal, MD, PhD. The database uses artificial intelligence (AI) to help researchers conduct complex diagnostic studies. The research is used to look the impact of eye disease on a patient's daily life and to improve the quality of life for those patients. Recently, three articles were published from the lab.
First, on August 16, 2022 the American Academy of Ophthalmology publication regarding two strategies, "Swedish Interactive Thresholding Algorithm (SITA) Standard (SS) and SITA Faster (SFR)", which were compared in "individuals undergoing standard automated perimetry (SAP) for the first time". SAP is a form of visual field testing using a computer program to see what the individual's visual field looks like. In this study, 74 random, perimetry-naive healthy individuals were tested. The test resulted in similarities between SS and SFR, but ophthalmologists should know researchers found that both strategies resulted in a large number of false positive rates among these individuals. To learn more click here.
The American Academy of Ophthalmology also published the "Association of an Objective Structural and Functional Reference Standard for Glaucoma with Quality-of-Life Outcomes" on August 26, 2022. The purpose of this study was to "compare self-reported quality of life (QoL) outcomes of patients diagnosed as normal, glaucoma suspect, and glaucoma based on an objective reference standard for glaucomatous optic neuropathy (GON)." This study used 1,884 eyes of 1,019 patients and the results are the worst QoL scores were associated with a glaucoma diagnosis from an objective reference standard. To learn more click here.
The most recent study published by the American Academy of Ophthalmology is "Comparison of 10-2 and 24-2 Perimetry to Diagnose Glaucoma Using OCT as an Independent Reference Standard" on September 6, 2022. The purpose was to compare the performance of 10-2 vs. 24-2 in the diagnosis of glaucoma. 339 individuals were used for this study and the results shows the 24-2 test had greater diagnostic accuracy for detecting glaucomatous damage than the 10-2 test did. To learn more click here.